Chemical Composition Analysis and Biofunctionality of Polygonatum sibiricum and Polygonatum odoratum Extracts


  • Wayne Liao Chang Gung University of Science and Technology
  • Jung-Ping Huang Department of Applied Cosmetology, Hung-Kuang University
  • Wen-Ying Huang Department of Applied Cosmetology, Hung-Kuang University


Polygonatum sibiricum, Polygonatum odoratum, Chemical composition, Antioxidant ability, Tyrosinase inhibition activity


Polygonatum sibiricum (P. sibiricum) and Polygonatum odoratum (P. odoratum) are commonly known Chinese herbal medicine sources. Although they had similar medical effects, the difference between these varieties was verified in this study. Liquid chromatography with tandem mass spectrometry (LC/MS/MS) was used to determine their chemical composition. P. sibiricum has seven chemical components, whereas P. odoratum has only five. Based on the DPPH radical scavenging activity analysis results, half maximal inhibitory concentration (IC50) values of P. sibiricum and P. odoratum were 4.23 and 18.3 mg/mL, respectively. The results of ABTS+ radical scavenging activity analysis showed that the IC50 values of P. sibiricum and P. odoratum were 4.77 and 19.3 mg/mL, respectively. Moreover, P. sibiricum had higher total phenolic content (10.0 mg of gallic acid / g of extract), and better reducing ability than P. odoratum. Again, P. sibiricum showed better tyrosinase inhibition ability than P. odoratum, and the IC50 values were 9.68 and 15.4 mg/mL, respectively. P. sibiricum was concluded to have better biofunctionality than P. odoratum.






Research Article or Brief Communication