Methods in the Synthesis and Conversion of 2,5-Bis-(hydroxylmethyl)furan from Bio-derived 5-Hydroxymethylfurfural and its Great Potential in Polymerization

Junhua Zhang, Ting Wang, Xing Tang, Lincai Peng, Junnan Wei, Lu Lin


To meet increasing demands for alternatives to fossil-based chemicals, environment-friendly and renewable energy materials are of great importance. Biomass-derived 2,5-bis-(hydroxylmethyl)furan (BHMF) has the potential to partly substitute petroleum-based aromatic diols during polymerization. This paper summarizes recent research on the synthesis of BHMF by the reaction of hydrogen from biomass-based 5-hydroxymethylfurfural through different reduction routes, including the Cannizzaro reaction, catalytic hydrogenation, and catalytic transfer hydrogenation. Applications of BHMF as a direct material and intermediate in fabricating polyurethane, self-healing materials, resins, and more, which utilize ring-opening, double-bond addition, and oxidation reactions, are discussed briefly. Additionally, the challenges and opportunities in the formation and application of BHMF in the future are discussed.


5-Hydroxymethylfurfural; 2,5-Bis-(hydroxylmethyl)furan; Catalytic transfer hydrogenation; Biomass-based polymer

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