Polymer Nanoparticles for Drug Delivery – Synthetic vs. Biopolymers?

Martin Gericke, Thomas Heinze

Abstract


Nanoparticles have a great prospect for therapeutic applications. They can protect drugs under physiological conditions and act as a matrix for directed delivery of drugs, e.g., to a specific tissue or cell type. Polymer-based nanomaterials are considered as highly effective in this regard. Their properties can be tailored to meet specific demands for given therapeutic purposes. Considering the high-quality standards placed on medical products, the question arises: Which type of polymer material should be employed? One might select synthetic polymer compounds, which are highly diverse in terms of the molecular structures and supramolecular architectures that can be created, or biopolymers such as polysaccharides that are renowned for their native biocompatibility.

Keywords


Nanoparticles; Polymers; Polysaccharides; Drug delivery; Biocompatibility; Interdisciplinary research

Full Text:

PDF


Welcome to BioResources! This online, peer-reviewed journal is devoted to the science and engineering of biomaterials and chemicals from lignocellulosic sources for new end uses and new capabilities. The editors of BioResources would be very happy to assist you during the process of submitting or reviewing articles. Please note that logging in is required in order to submit or review articles. Martin A. Hubbe, (919) 513-3022, hubbe@ncsu.edu; Lucian A. Lucia, (919) 515-7707, lucia-bioresources@ncsu.edu URLs: bioresourcesjournal.com; http://ncsu.edu/bioresources ISSN: 1930-2126